Registration Dossier
Registration Dossier
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EC number: 700-172-3 | CAS number: 634-55-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP, guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- yes
- Remarks:
- See chapter 13 of the final report
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- ethyl 2-cyano-3-oxobutanoate
- EC Number:
- 700-172-3
- Cas Number:
- 634-55-9
- Molecular formula:
- C7 H9 NO3
- IUPAC Name:
- ethyl 2-cyano-3-oxobutanoate
Constituent 1
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- < 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- ca. 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 10 - 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Any other information on results incl. tables
Endpoint |
NOEC |
LOEC |
EC50 |
Growth Rate |
< 1.0 mg/L |
1.0 mg/L |
10 – 100 mg/L |
AUC |
< 1.0 mg/L |
1.0 mg/L |
10 – 100 mg/L |
Yield |
< 1.0 mg/L |
1.0 mg/L |
10 – 100 mg/L |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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