Registration Dossier
Registration Dossier
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EC number: 905-898-6 | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results for the two major constituents the NOEC for the substance is estimated to be 3 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3 mg/L
Additional information
To determine the chronic toxicity of 2,2',2"-nitrilotriethanol to aquatic invertebrates, a non-GLP study following an internal method of the German Federal Environmental Agency was performed using a semi-static procedure (Kuehn et al./UBA 1989). The calculated NOEC value for Daphnia magna after an exposure period of 21 days in this study was 16 mg/l.
For DEA there is one valid BASF GLP semi-static study conducted 1992 according to the draft EEC guideline XI/681/86 "Prolonged toxicity study withDaphnia magna: Effects on reproduction" available. The NOEC after 21 days of exposure based on reproduction was determined to be 0.78 mg/L.
Since DEA is present in the substance at a maximum amount of 25% the NOEC for the substance is estimated to be 0.78/0.25= 3.12 mg/L
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