A mixture of: 2,4 -bis(N'-(4-methylphenyl)ureido)toluene; 2,6 -bis(N'-(4-methylphenyl)ureido)toluene

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

September 24, 1992 - September 25, 1992

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

This study has been performed according to OECD 115 (1981), EU Method A.5 (1984), proposed updated version of EU Method A.5 (November 1989) and according to GLP principles. Limited information available to verify the composition of the used test substance.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1992

Report date:

1992

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

(1981)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

(1984)

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

other: proposed updated version of EU Method A.5 (November 1989)

Deviations:

no

GLP compliance:

yes

Type of method:

ring method

Test material

Test material information

Constituent 1

Reference substance name:

A mixture of: 2,4 -bis(N'-(4-methylphenyl)ureido)toluene; 2,6 -bis(N'-(4-methylphenyl)ureido)toluene

EC Number:

411-070-0

EC Name:

A mixture of: 2,4 -bis(N'-(4-methylphenyl)ureido)toluene; 2,6 -bis(N'-(4-methylphenyl)ureido)toluene

Molecular formula:

C23H24N4O2

IUPAC Name:

3-(2-methyl-5-{[(4-methylphenyl)carbamoyl]amino}phenyl)-1-(4-methylphenyl)urea

Details on test material:

- Name of test material (as cited in study report): KY-ET
- Appearance: Light yellow solid
- Storage condition of test material: At room temperature in the dark

Results and discussion

Surface tension

Surface tension:

72.4 mN/m

Temp.:

20 °C

Remarks on result:

other: The saturated solution was clear and was obtained by centrifugation and by removal of floating particles by suction.

Any other information on results incl. tables

Calibration

The mean surface tension was determined to be 73.7 mN/m (measured at 19.8 -19.7 degrees Celsius). The calibration factor was therefore 72.63/73.7 = 0.985

Results individual measurements

Determination	Time expired [min]	Surface tension [mN/m]
		measured	mean	Mean corrected for calibration	Mean corrected for calibration and using Harkins and Jordan
1	26	74.8*	73.5	72.4	72.4
2	27	75.0*
3	29	73.7
4	29	73.4
5	30	73.5
6	31	73.6
7	32	73.4

*Not used in the calculation of the mean

Applicant's summary and conclusion

Conclusions:

The ring method was applied for the determination of the surface tension of the substance, in accordance with OECD 115 (1981), EU Method A.5 (1984), proposed updated version of EU Method A.5 (November 1989) and according to GLP principles. The surface tension of a saturated solution of the substance at 20°C was 72.4 mN/m. As this value is well below the cut-off value for surface active substances (60 mN/m), the substance is considered to be not surface active.