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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20.06.2022 - 15.08.2022
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2022
Report date:
2022

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
Water solubility (OECD 105, adopted on 27 July 1995, Method A.6 of Commission Regulation (EC) No. 440/2008)
GLP compliance:
no
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-hydroxydecanoic acid
EC Number:
611-068-1
Cas Number:
5393-81-7
Molecular formula:
C10-H20-O3
IUPAC Name:
2-hydroxydecanoic acid
Test material form:
solid
Details on test material:
Purity: ca. 99.1%
Specific details on test material used for the study:
white, crystalline solid

Results and discussion

Water solubilityopen allclose all
Key result
Water solubility:
ca. 708 mg/L
Conc. based on:
test mat.
Incubation duration:
ca. 24 h
Temp.:
23.5 °C
pH:
ca. 3.2
Key result
Water solubility:
>= 100 g/L
Conc. based on:
test mat.
Incubation duration:
ca. 24 h
Temp.:
235 °C
pH:
ca. 9
Details on results:
The water solubility of the test item was determined at approx. 23.5 °C and pH 3.2 to be 708 mg/L. For details, please see section “any other information on results incl. tables”.

Any other information on results incl. tables

The results can be found in the following table:


































Sample



Concentration



24 h-0.05



708



44 h-0.05



702



72 h-0.05



710



average



707



Standard deviation



4.2



Variation coefficient



0.6%



































Sample



Concentration



24 h-0.45



715



44 h-0.45



708



72 h-0.45



705



average



709



Standard deviation



5.1



Variation coefficient



0.7%



The water solubility "as it is" is 708 ± 4.4 mg/L.


 

Applicant's summary and conclusion

Conclusions:
Water solubility: 708 mg/L ((23.5 ± 0.5) °C, pH 3.2)
Water solubility: > 100 g/L ((23.5 ± 0.5) °C, pH 9)
Executive summary:

The water solubility of 2-Hydroxdecanoic acid was determined according to OECD Guideline 105 [adopted on 27 July 1995] and EU test method A.6 [Council Regulation (EC) No 440/2008] with the flask method.
Water solubility: 708 mg/L ((23.5 ± 0.5) °C, pH 3.2)
Water solubility: > 100 g/L ((23.5 ± 0.5) °C, pH 9)