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EC number: 611-068-1 | CAS number: 5393-81-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20.06.2022 - 15.08.2022
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 022
- Report date:
- 2022
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- Water solubility (OECD 105, adopted on 27 July 1995, Method A.6 of Commission Regulation (EC) No. 440/2008)
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- 2-hydroxydecanoic acid
- EC Number:
- 611-068-1
- Cas Number:
- 5393-81-7
- Molecular formula:
- C10-H20-O3
- IUPAC Name:
- 2-hydroxydecanoic acid
- Test material form:
- solid
- Details on test material:
- Purity: ca. 99.1%
Constituent 1
- Specific details on test material used for the study:
- white, crystalline solid
Results and discussion
Water solubilityopen allclose all
- Key result
- Water solubility:
- ca. 708 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- ca. 24 h
- Temp.:
- 23.5 °C
- pH:
- ca. 3.2
- Key result
- Water solubility:
- >= 100 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- ca. 24 h
- Temp.:
- 235 °C
- pH:
- ca. 9
- Details on results:
- The water solubility of the test item was determined at approx. 23.5 °C and pH 3.2 to be 708 mg/L. For details, please see section “any other information on results incl. tables”.
Any other information on results incl. tables
The results can be found in the following table:
Sample | Concentration |
24 h-0.05 | 708 |
44 h-0.05 | 702 |
72 h-0.05 | 710 |
average | 707 |
Standard deviation | 4.2 |
Variation coefficient | 0.6% |
Sample | Concentration |
24 h-0.45 | 715 |
44 h-0.45 | 708 |
72 h-0.45 | 705 |
average | 709 |
Standard deviation | 5.1 |
Variation coefficient | 0.7% |
The water solubility "as it is" is 708 ± 4.4 mg/L.
Applicant's summary and conclusion
- Conclusions:
- Water solubility: 708 mg/L ((23.5 ± 0.5) °C, pH 3.2)
Water solubility: > 100 g/L ((23.5 ± 0.5) °C, pH 9) - Executive summary:
The water solubility of 2-Hydroxdecanoic acid was determined according to OECD Guideline 105 [adopted on 27 July 1995] and EU test method A.6 [Council Regulation (EC) No 440/2008] with the flask method.
Water solubility: 708 mg/L ((23.5 ± 0.5) °C, pH 3.2)
Water solubility: > 100 g/L ((23.5 ± 0.5) °C, pH 9)
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