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EC number: 954-793-1
CAS number: -
In the study the test item formulated in PG was assessed for its possible skin sensitising potential.
For this purpose a local lymph node assay was performed using test item concentrations of 5, 10, and 25% (w/w).
The animals did not show any signs of systemic toxicity or local skin irritation during the course of the study and no cases of mortality were observed.
In this study Stimulation Indices (S.I.) of 1.60, 1.06, and 1.14 were determined with the test item at concentrations of 5, 10, and 25% (w/w) in PG, respectively.
The test item was not a skin sensitiser under the test conditions of this study.
For this endpoint a one-to-one read across was performed to a chemical similar compound of the same chemical class with a comparable phys. chem. profile and similar response in biological assays. The relevant study was performed according to GLP and the methods applied are fully compliant with OECD TG 429. The result obtained for the read across from the source compound was negative.
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