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EC number: 954-793-1
CAS number: -
No adverse effects observed.
The objective of the present study was to identify potential toxic effects of the test item after single oral administration of 2000 mg/kg body weight to rats.
This study was performed according to GLP and the methods applied are fully compliant with OECD TG 423. For this assay a starting dose of 2000 mg/kg body weight was selected.
Mortality and clinical signs were monitored for at least 6 hours after administration and then daily. All animals were weighed before treatment (day 1) and on days 2, 4, 6, 8, 11, 13, and 15. At the end of the observation period, all surviving rats were sacrificed and subjected to a detailed necropsy.
No mortality occurred during the course of this study. No clinical signs of toxicity were observed.
The body weight development was inconspicuous throughout the study. The gross pathological examination revealed no organ alterations.
The test item has no acute toxic potential under the conditions of the present study, and the LD50 value is higher than 2000 mg/kg after single oral administration in female rats.
For this endpoint a one-to-one read across was performed to a chemical similar compound of the same chemical class with a comparable phys. chem. profile and similar response in biological assays. The relevant study was performed according to GLP and the methods applied are fully compliant with OECD TG 423. The result obtained for the read across from the source compound was LD50 > 2000 mg/kg bw.
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