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EC number: 618-687-6
CAS number: 909709-42-8
The test item was tested for acute toxicity in rats after single oral
administration of 2000 mg/kg body weight. Directly before administration
the test material was prepared with aqueous Methocel K4M Premium
solution as vehicle. This GLP study was performed according to the OECD
No signs of intoxication occurred after treatment and all the rats
survived the observation period. Body weight development of the treated
rats was normal. At necropsy, no organ alterations were seen.
For regulatory purposes, the median lethal dose (LD50), after an
observation period of 15 days can be declared as > 2000 mg/kg.
This study was performed according to GLP and is fully compliant OECD TG
423. Based on the result of this study, it is concluded that the test
material has no acute toxic potential and that the LD50 value is higher
than 2000 mg/kg after single oral administration in rats.
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