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EC number: 618-687-6
CAS number: 909709-42-8
This study was performed with a structural analogue substance according
to GLP and is fully compliant OECD TG 423. Based on the result of this
study, it is concluded that the test material has no acute toxic
potential and that the LD50 value is higher than 2000 mg/kg after single
oral administration in rats.
The test item was tested for acute toxicity in rats after single oral
administration of 2000 mg/kg body weight. Directly before administration
the test material was prepared with aqueous Methocel K4M Premium
solution as vehicle. This GLP study was performed according to the OECD
No signs of intoxication occurred after treatment and all the rats
survived the observation period. Body weight development of the treated
rats was normal. At necropsy, no organ alterations were seen.
For regulatory purposes, the median lethal dose (LD50), after an
observation period of 15 days can be declared as > 2000 mg/kg.
This study was performed according to GLP and is fully compliant OECD TG
423. Based on the result of this study, it is concluded that the test
material has no acute toxic potential and that the LD50 value is higher
than 2000 mg/kg after single oral administration in rats.
Based on the data provided, the test item is not classified for acute
oral toxicity according to REACH Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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