Registration Dossier
Registration Dossier
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EC number: 424-510-1 | CAS number: 220150-59-4
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
Water solubility 655 ± 36 g/l
Key value for chemical safety assessment
Additional information
Solubility of the test item in water was determined in an experimental study according to the OECD Guideline 105 (1981) and the EU Method A.6 (1992). A preliminary test predicted that the solubility of the test item would be between 10 and 200 mg/l and determined the shake method as the most appropriate test for solubility for this substance. 6 Erlenmeyer flasks, each containing 48 g of test item in 30 ml of double distilled water, were shaken in a water bath at 30 °C for either 24, 48 or 72 hours, then were incubated for a further 24 hours at 20 °C. Samples were centrifuged and filtered, then alquiots of dilutions from each flask were analysed using a spectrophotometer. Absorbance from 190 to 1100 nm was plotted graphically to determine a calibration curve. No significant differences were found between duplicates which were shaken for 48 and 72 hours, therefore the study was determined to be valid.
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