Tar bases, coal, lutidine fraction

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Study initiation date: 21 December 2015, Experimental start date: 18 January 2016, Experimental completion date: 19 January 2016

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Version / remarks:

1995 (differential scanning calorimetry method)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

Commission Regulation (EC) No 440/2008, dated May 30, 2008

Deviations:

no

GLP compliance:

no

Remarks:

However, the study was performed in a test facility which has been certified to be in compliance with the principles of GLP.

Type of method:

differential scanning calorimetry

Remarks:

DSC

Boiling pt.:

154 °C

Atm. press.:

101.2 kPa

Decomposition:

no

Remarks on result:

other: Significant vaporisation/boiling was observed to commence at 121 °C (394 K) and end at 174 °C (447 K), with the boiling temperature (extrapolated from the maximum rate of vapourisation) of the test item determined to be 154 °C (427 K).

Boiling pt.:

427 K

Atm. press.:

101.2 kPa

Decomposition:

no

The interpretation of the thermographic data for determinations 1 to 6 inclusive is shown in Table 1.

Table 1: Determinations 1-6

Determination	Thermal Event	Interpretation	Temperature
			°C	K
1	Approximate onset of endotherm.	Approximate onset of boiling of the test item.	122.51	396
	Extrapolated onset of endotherm.	Boiling temperature.	154.25	427
	Approximate endset of endotherm.	Approximate endset of boiling of the test item.	172.12	445
2	Approximate onset of endotherm.	Approximate onset of boiling of the test item.	120.71	393
	Extrapolated onset of endotherm.	Boiling temperature.	154.22	427
	Approximate endset of endotherm.	Approximate endset of boiling of the test item.	173.76	447
3	Extrapolated onset of endotherm.	Extrapolated maximum rate of sample evaporation/vaporisation.	149.44	423
4	Extrapolated onset of endotherm.	Extrapolated maximum rate of sample evaporation/vaporisation.	147.88	421
5	Extrapolated onset of endotherm.	Extrapolated maximum rate of sample evaporation/vaporisation.	130.23	403
6	Extrapolated onset of endotherm.	Extrapolated maximum rate of sample evaporation/vaporisation.	146.26	419

Conclusions:

In a reliable and conclusive study according to OECD TG 103 (1995) and Method A.2 (EC) No 440/2008, significant vaporisation/boiling was observed to commence at 121 °C (394 K) and end at 174 °C (447 K), with the boiling temperature (extrapolated from the maximum rate of vaporisation) of the test item determined to be 154 °C (427 K), at an atmospheric pressure of 101.2 kPa.

Executive summary:

The boiling point of the test item was investigated in a non-GLP study using the differential scanning calorimetry (DSC) method according to the OECD TG 103 (1995) and EU A.2 (Commission Regulation (EC) No 440/2008) protocols. The experiment is considered relevant, adequate and conclusive.

The temperature accuracy of the DSC was checked prior to testing with indium and zinc. Aliquots of test item (0.0072-0.0086 g) were placed in aluminium crucibles. Pre-perforated lids used for determination 1 and 2, while manually pierced lids were used in determinations 3 to 6. The initial Temperature program of 20 °C was increased by 20 °C/min. The atmospheric pressure was 101.2 kPa. Atmosphere during determinations 1 to 4 inclusive consisted of air (static) while for determinations 5 and 6 nitrogen was used.

The boiling temperature of the test item, extrapolated from the endotherms achieved, was 154 °C (427 K), from determination 1 and determination 2. Significant vaporization/boiling was observed to commence at 121 °C (394 K) and end at 174 °C (447 K), with the boiling temperature (extrapolated from the maximum rate of vaporization) of the test item determined to be 154 °C (427 K).

From comparison of the endotherm profiles obtained from samples analyzed using pre perforated crucible lids (which allow self-pressurisation up to the boiling temperature) and those using manually pierced crucible lids (i.e. an open system), it can be confirmed that the observed thermal event was a true boiling temperature for the test item.

In result the boiling temperature of the test item extrapolated from the maximum rate of vaporization and from the endotherms achieved was item determined to be 154 °C (427 K). According to a scheme this places the test item in the “Low” volatility band (> 150 °C) for occupational exposure estimation (ECHA R.14, Table R.14-11, p 28).

Description of key information

In a valid, reliable and conclusive study according to OECD TG 103 (1995) and Method A.2 (EC) No 440/2008, significant vaporisation/boiling was observed to commence at 121 °C (394 K) and end at 174 °C (447 K), with the boiling temperature (extrapolated from the maximum rate of vaporisation) of the test item determined to be 154 °C (427 K), at an atmospheric pressure of 101.2 kPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

154 °C