Registration Dossier
Registration Dossier
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EC number: 240-968-3 | CAS number: 16919-19-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 988
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: not specified
- GLP compliance:
- no
Test material
- Reference substance name:
- Ammonium hexafluorosilicate
- EC Number:
- 240-968-3
- EC Name:
- Ammonium hexafluorosilicate
- Cas Number:
- 16919-19-0
- Molecular formula:
- F6Si.2H4N
- IUPAC Name:
- diammonium hexafluorosilicate
- Test material form:
- solid: particulate/powder
1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Amount / concentration applied:
- 1g /rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- other:
- Basis:
- other: not specified
- Time point:
- other: not specified
- Score:
- > 3 - < 6
- Max. score:
- 6
- Reversibility:
- not specified
- Remarks on result:
- probability of moderate irritation
- Remarks:
- edema, scale
- Irritant / corrosive response data:
- edema, scale, Draize index 3-6
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritant) based on GHS criteria
- Conclusions:
- The test substance is irritant on rabbit skin.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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