Registration Dossier
Registration Dossier
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EC number: 281-658-8 | CAS number: 84012-13-5 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Arctium lappa, Compositae.
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, described in sufficient detail.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Arctium lappa, ext.
- EC Number:
- 281-658-8
- EC Name:
- Arctium lappa, ext.
- Cas Number:
- 84012-13-5
- IUPAC Name:
- Arctium lappa, ext.
- Details on test material:
- - Name of test material (as cited in study report): Klettenfruchtextrakt conc.
- Physical state / colour / odour: viscous liquid, golden brown, fruity odour
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Source of inoculum: activated sludge from treatment plant Ottendorf-Okrilla
- Method of cultivation: aerated, sedimented, decanted, homogenized - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 60 mg/L
- Based on:
- test mat.
- Initial conc.:
- 94 mg/L
- Based on:
- ThOD/L
- Details on study design:
- TEST CONDITIONS
- Test temperature: 20.0 +- 1°C
- pH: controlled
- Cell concentration: 10exp8 cells/L
TEST SYSTEM
- Number of culture flasks/concentration: 2
Reference substance
- Reference substance:
- acetic acid, sodium salt
- Remarks:
- 100 mg/L, 47 mg BOD/L
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 97.8
- Sampling time:
- 28 d
- Details on results:
- Within 10-day window 68% degradation were observed.
Nitrification was not observed.
BOD5 / COD results
- Results with reference substance:
- 100% after 14 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
The biological degradability of Arctium lappa extract was examined in a Manometric Respirometry Test according to OECD Guideline 301 F. The test substance was degraded to 97.8% after 28 days. Within the 10 -days window degradation was 68%.
Based on the results, the test substance is classified as readily biodegradable, fulfilling the 10 -days window criterion.
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