Registration Dossier
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EC number: 946-333-3 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The biodegradation potential of the target substance, Schiff bases, benzylidene, C16-18 (even
numbered) and C18-unsaturated alkyl was also investigated using the CATALOGIC 301C QSAR model.
The target substance is a multiconstituent substance, and was assessed as a mixture using all seven
analytically-identified constituents. All constituents and the mixture (target substance) were found to be
readily biodegradable. The target substance (mixture) was predicted to have a 28 -day biodegradation of approximetaly 72% (readily biodegradable). This prediction supports the read-across prediction made using the OECD
QSAR Toolbox. The prediction satisfies the OECD principles for QSAR validation and is a reliable result that can be used for risk assessment and classification purposes.
Schiff bases, benzylidene, C16-18 (even numbered) and C18-unsaturated alkyl, is a multicomponent
substance, was also assessed for its biodegradation potential as mixture using OECD QSAR Toolbox
v4.1, 2017. Seven constituents have been identified for the target substance (TS). Experimental
data were found only for one constituent, benzaldehyde, contained at 2 wt.% in the TS. For each of
the six remaining constituents, prediction was made using read-across. Primary categorization was
done using the ECOSAR profile of "Schiff Bases-Azomethine", which was common to all six
constituents. Sub-categorization was done to further refine the prediction primarily based on
structural similarity. All six constituents of the TS are predicted to be readily biodegradable and the
seventh, benzaldehyde, is readily biodegradable as well, by experimental data. The mixture's biodegradability was then predicted using the individual constituents' data and the mixture is predicted to have approximately 72% biodegradation (readily biodegradable) as well.
prediction as well is readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
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