N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid

Health surveillance data

Administrative data

Endpoint:

health surveillance data

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study meets generally accepted scientific principles, acceptable for assessment. Medical surveillance data.

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

2009

Materials and methods

Study type:

medical monitoring

Endpoint addressed:

skin irritation / corrosion

eye irritation

respiratory irritation

skin sensitisation

Principles of method if other than guideline:

Routine medical check up of workers involved in production of the test substance.

GLP compliance:

no

Test material

Test material information

Constituent 1

Method

Type of population:

occupational

Ethical approval:

not applicable

Details on study design:

Routine medical check up of 25 workers of a production plant, examined by occupational medicine department every 3 years. The last check up was carried out in 2009. Workers were examined for disorders like irritation of the respiratory tract, the eyes, skin, allergic disorders or sensitisation related to contact with the test substance.

Results and discussion

Results:

During these examinations no observations of disorders such as irritation of the respiratory tract, the eyes, the skin, allergic reactions or sensitisation have been made, which were related to the test substance.

Applicant's summary and conclusion

Conclusions:

The test substance does not induce irritating or sensitising effects in workers involved in the production of the substance.