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EC number: 201-539-6
CAS number: 84-54-8
Test and Control Article Identity
Test and control article identity
Blank corrected data
Mean of aliquots
84-54 -8, solid
The ocular irritation potential of
test article was determined according to the OECD 492 test guideline.
The MatTek EpiOcular™ model was used to assess the potential ocular
irritation of the test article by determining the viability of the
tissues following exposure to the test article via MTT. The objective of
this study was to assess the ocular irritation potential of test
article. Tissues were exposed to test article and controls for ~6 hours,
followed by a ~25 minute post-soak and approximately 18 hour recovery
after the post-soak. The viability of each tissue was determined by MTT
The MTT data show the assay quality
controls were met, as the OD of the negative control tissues was between
0.8 to 2.5 in run 1. Also, the positive control, methyl acetate, reduced
tissue viability to be below 50% of negative control (for 6 hour
exposures with solids) in run one.The mean % tissue viability of the test
chemical was determined to be 109.5%.
Hence, under the experimental test
conditions it was concluded that the test chemical was considered to be
not irritating to the MatTek EpiOcular Tissue Model OCL-200 and being
classified as “Not classified’’.
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