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EC number: 201-539-6
CAS number: 84-54-8
Test and Control Article Identity
Test and control article identity
Blank corrected data
Mean of aliquots
The dermal irritation potential of
test article was determined according to the OECD 439 In Vitro Skin
Irritation: Reconstructed Human Epidermis Test Method”. The MatTek
EpiDerm™ model was used to assess the potential dermal irritation of the
test article by determining the viability of the tissues following
exposure to the test article via MTT. The objective of this study was to
assess the dermal irritation potential of test article Tissues were
exposed to test article and controls for ~one hour, followed by a 42
hour post-exposure recovery period. The viability of each tissue was
determined by MTT assay.
The MTT data shows that the assay
quality controls were met, as the OD of the negative control tissues was
between 1.195 and 1.430. Also, the positive control, 5% sodium dodecyl
sulfate (SDS), reduced tissue viability to 4.5% of negative control.
The Mean % tissue viability compared
to negative control (n=3) of the test chemical was determined to be
Hence, under the experimental test
conditions it was concluded that the test chemical was considered to be
not irritating to the human skin and being classified as “Not
Classified'' as per CLP Regulation.
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