[1,3-dihydro-5,6-bis[[(2-hydroxy-1-naphthyl)methylene]amino]-2H-benzimidazol-2-onato(2-)-N5,N6,O5,O6]nickel

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

test procedure similar to OECD 105

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Reference

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Remarks:

Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: Analytical Expert Group ETAD

Medium:

n-octanol

Solubility:

200 µg/L

Temp.:

23 °C

Remarks on result:

other: mean of 3 measurements

Test substance stable:

yes

_{The solubility of the sample Pigment Orange 68 in n-octanol at ambient temperature, determined under the conditions as mentioned above, is 200 µg/L (mean, n = 3, sigma= 6).}

Table 1: Individual results

	Adsorption (d = 10 cm)	µg/L
a1	0.111	195
a2	0.113	199
a3	0.117	206

 

Cross-reference 2

Reason / purpose for cross-reference:

reference to same study

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Remarks:

Procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer); method similar to Annex V, A.8, 1.6.1, Directive 67/548/EEC

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: ETAD Analytical Expert Group

Version / remarks:

method for substances with very low solubility in both, water and n-octanol

Principles of method if other than guideline:

Based on the determined solubilities in water and in n-octanol the partition coefficient is estimated

Type of method:

estimation method (solubility ratio)

Partition coefficient type:

octanol-water

Type:

log Pow

Partition coefficient:

1.2

Temp.:

23 °C

pH:

6.2

Type:

Pow

Partition coefficient:

16

Temp.:

23 °C

pH:

6.2

Solubility of Pigment Orange 68 in n-octanol: 200 µg/L

Water solubility of Pigment Orange 68: 12.5 µg/L

P_{ow PO 68} = 16

log P_{ow PO 68} = 1.20

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2015

Report date:

2015

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

yes

Remarks:

modified takint into account the very low solubility of the test substance

Principles of method if other than guideline:

Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

[1,3-dihydro-5,6-bis[[(2-hydroxy-1-naphthyl)methylene]amino]-2H-benzimidazol-2-onato(2-)-N5,N6,O5,O6]nickel

EC Number:

255-965-2

EC Name:

[1,3-dihydro-5,6-bis[[(2-hydroxy-1-naphthyl)methylene]amino]-2H-benzimidazol-2-onato(2-)-N5,N6,O5,O6]nickel

Cas Number:

42844-93-9

Molecular formula:

C29H18N4NiO3

IUPAC Name:

Nickel, [1,3-dihydro-5,6-bis[[[2-(hydroxy-kO)-1-naphthalenyl]methylene]amino-kN]-2H-benzimidazol-2-onato(2-)]-, (SP-4-2)-

Test material form:

solid: nanoform

Results and discussion

Water solubility

Water solubility:

12.5 µg/L

Temp.:

23 °C

pH:

6.2

Remarks on result:

other: mean of 2 measurements

Any other information on results incl. tables

_{The solubility of the sample Pigment Orange 68 in water at ambient temperature, determined under the conditions as mentioned above, is 12.5 µg/L (mean, n = 2, sigma = 0.5).}

Table 1: Individual results

	Absorption (d = 10 cm)	µg/L
a1	0.0069	12.1
a2	0.0073	12.8

Applicant's summary and conclusion

Conclusions:

the test substance is practically insoluble in water (< 0.1 mg/L)