Registration Dossier
Registration Dossier
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EC number: 606-274-3 | CAS number: 192389-48-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
After 48 hrs an EC-0 of >= 92.4 mg/l was measured. The result is expressed in terms of nominal concentrations (Bruns, 2002).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 92.4 mg/L
Additional information
"Should read > 92.4 mg/l"
The substance hydrolyses quickly in water with a hydrolysis half-life of 0.1 hour. As the test solution was stirred 24 h hours before application, the test was assumedly rather performed with the hydrolysis products. Analytical monitoring was performed by TOC determination which does not distinguish between the starting and its hydrolysis products.
Acute toxicity to Daphnia magna was determined in accordance with the Council Regulation (EC) No 440/2008, Method C.2 'Acute
toxicity for Daphnia' (2008) which is in most parts equivalent to the OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). In
order to test acute toxicity to invertebrates of the substance, Daphnia Magna was exposed to a limit test concentration of nominally 100
mg/L of test material dissolved in dilution water. Auxiliaries used to prepare the test media were an ultrasonic turrax and a magnetic stirrer. Observations were made on the swimming ability and the immobilisation rate, respectively, after 24 and 48 hours of exposure. After 48 hrs an EC-0 of >= 92.4 mg/l was measured and the result is expressed in terms of nominal concentrations.
This toxicity study is classified as acceptable and satisfies the guideline requirements for the acute Daphnia study. The analytical monitoring of the hydrolytical unstable test substance was performed with TOC determination.
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