Registration Dossier
Registration Dossier
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EC number: 203-786-5 | CAS number: 110-63-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 hour Effect Concentration 50% (48h EC50, mobility): 813 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 813 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 80 mg/L
Additional information
The acute toxicity of 1,4 -Butanediol to aquatic invertebrates (Daphnia magna) has been tested according to a number of guideline and non-guideline methods under GLP and non-GLP conditions. Test results with a Klimisch score of at least 2 yielded a 48h EC50 value of 813 mg/L (Hüls AG, 1995) and >1000 mg/L (NITE Japan, 1996), a 48h LC50 of 15000 mg/L (DuPont, 1982), a 48h LC0 value of 7000 mg/L (DuPont, 1982), and a 48h EC0 value of 500 mg/L and EC50 value of >500 mg/L (BASF, 1988). These results indicate that 1,4 -Butanediol exhibits a low order of acute toxicity to aquatic invertebrates.
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