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EC number: 236-671-3 | CAS number: 13463-41-7
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Oral: LC50=60mg/kg, NOEC=31.2mg/kg
Dietary: EC50=1110ppm, NOEC=492ppm
Key value for chemical safety assessment
Additional information
The information contained within this robust summary document comes from studies which are in the ownership of Arch Chemicals Inc. and which are protected in several regions globally. This information may not be used for any purpose other than in support of the Chemical safety Report submitted by Arch Chemicals Inc. under RegulationEC 1907/2006.
Acute oral toxicity and short-term toxicity studies in the Northern Bobwhite and the Mallard are presented inTable58. These studies show significant tolerance to pyrithiones by birds. This allied to the low potential for bio-accumulation or bio-concentration in the food chain to birds, indicates that further testing is unnecessary.
Table58:Toxicity to birds
Guideline / |
Species |
Endpoint / |
Exposure |
Results [mg/kg dry soil] |
Remarks |
Reference |
|||
Design |
duration |
NOEC |
LOEC |
EC/LC50 |
|||||
EPA FIFRA Guideline 71-1 |
Northern Bobwhite, Colinus virginianus |
Mortality |
Oral 31.2, 62.5, 125, 250, 500, and 1000 mg/Kg bw |
14 days |
31.2 mg/kg |
|
60 mg/kg |
|
Campbell, Beavers & Jaber (1993) Unpublished study |
OECD 205 |
Northern Bobwhite, Colinus virginianus |
Mortality |
Dietary 275, 492, 878, 1568, 2800, 5000 ppm (nominal) in diet 238, 468, 920, 1640, 2990, 5420 ppm (measured) in diet |
8 days |
LC0– 492 ppm |
|
LC50– 1110 ppm
|
|
Campbell, Beavers (1994) Unpublished study |
OECD 205, EPA FIFRA 71-2 |
Mallard, Anas platyrhynchos |
Mortality |
Dietary 275, 492, 878, 1568, 2800, 5000 ppm (nominal) in diet 238, 468, 920, 1640, 2990, 5420 ppm (measured) in diet |
8 days |
LC0- 1568ppm
|
|
LC50- >5000ppm
|
|
Campbell, Beavers & Jaber (1994) Unpublished study
|
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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