Registration Dossier
Registration Dossier
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EC number: 918-139-9 | CAS number: 1228577-90-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Ortho-toluene diamine, propoxylated was tested in the Guinea Pig Maximization Test (GPMT) on 15 female test animals (10 for the test item group, 5 control animals) for its skin sensitizing properties, according to the OECD Guideline 406. Concentrations of 5% (intradermal induction), 50% (topical induction and first challenge) and 25% (second challenge) of the test material in PEG 400 were used. Under the conditions of the test Ortho-toluene diamine, propoxylated was shown to exhibit no skin sensitization potential.
Migrated from Short description of key information:
Non-sensitiser using the guinea pig maximization test (GPMT), OECD 406
Justification for classification or non-classification
Results do not warrant classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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