Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-102-5 | CAS number: 7439-93-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity test in fish with
lithium is not available. Consequently, read-across was applied using
study results obtained from lithium hydroxide monohydrate. In an 96-h
acute toxicity test in Zebrafish (Danio rerio) the 96h LC50 for lithium
hydroxide monohydrate based on mortality was determined to be 109 mg/L.
Based on a read across approach, the calculated LC50 value for lithium
metal was 18 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 18 mg/L
Additional information
Short-term toxicity test in fish with lithium is not available. Consequently, read-across was applied using study results obtained from lithium hydroxide monohydrate. The acute toxic effects of lithium hydroxide monohydrate to Zebrafish (Danio rerio) over a 96-hour static exposure period were assessed according to OECD guideline 203. For the range-finding test the test solutions were prepared in a dilution series from a stock solution of 100 mg/L of the test item in tap water. For the definitive test as limit test and the definitive test with five test concentrations the test solutions were prepared by direct transfer of weighted samples in various amounts of the test item into the tap water in the test vessels.
In this 96-h fish acute toxicity test with Zebrafish (Danio rerio) the 96h LC50 for Lithium hydroxide monohydrate based on mortality was determined to be 109 mg/L.
Based on a read-across approach, the calculated LC50 value for lithium metal was 18 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
