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EC number: 261-819-9 | CAS number: 59587-44-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects on aquatic algae up to the limit of water solubility, read across
Key value for chemical safety assessment
Additional information
Data on the acute toxicity of 2-ethylhexanol nonanoate (CAS
59587-44-9) to aquatic algae are not available. The assessment was
therefore based on studies conducted with the structurally similar
substances Fatty acids, C8-16, 2-ethylhexyl esters (CAS 135800-37-2) and
Octyl octanoate (CAS 2306-88-9) as part of a read across approach, which
is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5.
Further justification is given within the overall summary chapter
6.1. and within the analgoue justification section 13.
The toxicity of Fatty acids, C8-16, 2-ethylhexyl esters (CAS
135800-37-2) was tested in a limit test according to EU-Method C.3
(Wierich 1998). Desmodesmus subspicatus was exposed to a filtered
solution with a nominal test substance concentration of 100 mg/L. The
filtered solution showed no significant inhibition of algae growth or
growth rate which means that the water soluble part of the test
substance turned out not to be toxic. With a more or less homogenous
emulsion of test material high inhibitions of algae growth and growth
rate were observed (75.7% and 42.6% respectively). This observed
inhibition in presence of undissolved test substance can be accounted to
physical, but not biological influences and a ErC50(72 h) > 100 mg/L
could be stated. The results are supported by a study on the toxicity of
octyl octanoate (CAS No. 2306-88-9) accomplished according to OECD
Guideline 201 and GLP (Caduff, 2013) The test organism Desmodesmus
subspicatus was exposed to the test substance at a nominal loading of
100 mg/L, prepared as water soluble fractions (WSF), for 72 hours. No
significant effect on algal growth was observed. The EL50 based on
growth rate was determined to be > 100 mg/L. Thus, based on the above
mentioned result, and due to the structural and profile similarities of
the substances, as are explained with in the overall endpoint summary
6.1 it can be concluded that no toxicological effects on aquatic algae
are expected up to the limit of water solubility for 2-ethylhexanol
nonanoate (CAS 59587-44-9).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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