Registration Dossier
Registration Dossier
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EC number: 261-819-9 | CAS number: 59587-44-9
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects observed up to the limit of water solubility.
Key value for chemical safety assessment
Additional information
Data on the long-term toxicity of 2-ethylhexanol nonanoate (CAS
59587-44-9) to aquatic organisms are not available. The assessment was
therefore based on studies conducted with the structurally similar
substance Isopropyl myristrate (CAS 110-27-0) for which data is
available, as part of a read across approach, which is in accordance
with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Further justification
is given within the overall summary chapter 6.1 and within the analogue
justification.
The chronic toxicity of Isopropyl myristrate (CAS 110-27-0) to Daphnia
magna was tested according to OECD 202 (Scholz 1995) at 1 and 100 mg/L
(nominal). After prolonged stirring, the test substance was filtered
through glass fibre filter. No effects on mortality or reproduction were
detected at both test substance concentrations. Therefore, the
NOEC(reproduction, 21d) is >= 100 mg/L.
Thus, based on the above mentioned result, and due to the structural and
profile similarities of the substances, as are explained with in the
overall endpoint summary 6.1 it can be concluded that no chronic
toxicological effects on aquatic invertebrates are expected up to the
limit of water solubility for 2-ethylhexanol nonanoate (CAS 59587-44-9).
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