Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 285-998-8
CAS number: 85186-15-8
substance was assayed for the mutagenicity by the Bacterial Reverse
Mutation Test. The test was performed according to the EU method B.13/14
Mutagenicity – Reverse mutation test using bacteria,which is analogous
to the OECD Guideline 471.
indicator Salmonella typhimurium strains TA 98, TA 100, TA 1535,
TA 1537 and one indicator Escherichia coli WP2 uvrA strain were
used. The test substance was diluted in water for injection and assayed
in doses of 100 - 2300 mg per plate, which were applied to plates in
volume of 0.1 mL.
were performed without as well as with metabolic activation with a
supernatant of rat liver and a mixture of cofactors. The first
experiments were performed without and the second experiments with 30
minutes of pre-incubation at 37±1 °C and shaking.
arrangement given above, the test substance, was non-mutagenic for all
the used tester strains without as well as with metabolic activation.
Pre-incubation had no influence on study results.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again