Registration Dossier
Registration Dossier
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EC number: 209-388-8 | CAS number: 575-61-1
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Predicted value from (Q)SAR model.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- publication
- Title:
- Development toxicity
- Author:
- CAESAR (version 2.1.6)
- Bibliographic source:
- VEGA NIC
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: General model for estimating the development toxicity
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- 3-benzylidenephthalide
- EC Number:
- 209-388-8
- EC Name:
- 3-benzylidenephthalide
- Cas Number:
- 575-61-1
- Molecular formula:
- C15H10O2
- IUPAC Name:
- 3-benzylidene-2-benzofuran-1-one
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
Results: maternal animals
Maternal developmental toxicity
- Details on maternal toxic effects:
- Maternal toxic effects:no data
Effect levels (maternal animals)
- Dose descriptor:
- other:
- Based on:
- test mat.
- Basis for effect level:
- other: developmental toxicity
Results (fetuses)
- Details on embryotoxic / teratogenic effects:
- Embryotoxic / teratogenic effects:no data
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- The prediction is toxicant and the result appears reliable. By contrast, only moderately similar compounds in the training set have been found.
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