Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-472-8 | CAS number: 107-20-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of chloroacetaldehyde to the bacterium Pseudomonas putida was determined in a growth inhibition test according to the method described in the German Standard DIN 38412 Teil 8 and the International Standard ISO 10712. The study was carried out in according with the OECD principles of Good Laboratory Practice.
The concentrations of chloroacetyldehyde tested were 0, 6.5, 11, 20, 36, 62 and 111 mg/L. The concentrations given are nominal concentrations of chloroacetaldehyde. The growth was determined after 15.5 hours incubation at 23 +/- 1 °C by measuring the increase in absorbancy of the culture at 605 nm.
The effect values and their 95% confidence interval were calculated by a parametric model.
The EC10 with respect to bacterial growth after 15.5 hours was found to be 36.9 mg/L with a 95% confidence interval of 34.6-39.4 mg/L. This corresponds to an EC10 value of 17.0 mg/L (16.2-18.4 mg/L) with respect to the active ingredient.
The EC50 with respect to bacterial growth was found to be 44.7 mg/L with a 95% confidence interval of 35.1-57.0 mg/L. This corresponds to an EC50 value of 20.9 mg/L (16.4-26.7 mg/L) with respect to the active ingredient.
The test was valid as the increase in the control growth was sufficient and the EC50 of the reference substance 3,5-dichlorophenol had the expected value of 21.0 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 20.9 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
