Registration Dossier
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EC number: 700-626-0 | CAS number: 1073607-50-7
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: CTL SOP No.417
- Principles of method if other than guideline:
- CTL SOP No.417 is conducted initially using a visual microscope and is then undertaken more formally using a Laser Diffraction Particle Size Analyser.
- GLP compliance:
- yes (incl. QA statement)
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 2-[(1E)-2-[(3Z)-2-chloro-3-{2-[(2E)-1,1-dimethyl-3-(4-sulfobutyl)-1H,2H,3H-benzo[e]indol-2-ylidene]ethylidene}cyclohex-1-en-1-yl]ethenyl]-1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-3-ium amine
- EC Number:
- 700-626-0
- Cas Number:
- 1073607-50-7
- Molecular formula:
- C46 H50 Cl N2 O6 S2 . H4 N
- IUPAC Name:
- 2-[(1E)-2-[(3Z)-2-chloro-3-{2-[(2E)-1,1-dimethyl-3-(4-sulfobutyl)-1H,2H,3H-benzo[e]indol-2-ylidene]ethylidene}cyclohex-1-en-1-yl]ethenyl]-1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-3-ium amine
- Details on test material:
- As the sample is a dye the analysis was carried out using the ‘wet’, small volume dispersion system. Several solvents were tried, in order to determine a suitable medium that provided maximum dispersability, but with minimum solubility. Toluene was finally selected as the most suitable dispersant.
Constituent 1
Results and discussion
Particle sizeopen allclose all
- Percentile:
- D50
- Mean:
- 12.563 µm
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
- Percentile:
- D10
- Mean:
- < 4.231 µm
- St. dev.:
- 0.67
- Remarks on result:
- other: % relative standard deviation
- Percentile:
- D50
- Mean:
- < 11.104 µm
- St. dev.:
- 1.18
- Remarks on result:
- other: % relative standard deviation
- Percentile:
- D90
- Mean:
- < 34.133 µm
- St. dev.:
- 0.66
- Remarks on result:
- other: % relative standard deviation
Any other information on results incl. tables
volume weighted mean: 16.368µm
mode: 10.615µm
44.34% by volume of sample was seen to be <10.00µm. However, related to the low toxicity profilie and the use of a P3/P2 respiratory protection filter, no inhalation exposure is of concern.
Applicant's summary and conclusion
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