Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-157-3 | CAS number: 2378-02-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1986
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- in lack of translation the method remains unlear
- GLP compliance:
- no
Test material
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- inhalation
- Duration of exposure:
- 2 h
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 10 230 mg/m³ air
- Based on:
- test mat.
- Exp. duration:
- 2 h
- Remarks on result:
- other: details of toxic effect not reported ; only LC50 value was reported.
Any other information on results incl. tables
Details of toxic effects not reported other than lethal dose value.
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- The reliability of the data reported for acute inhalation toxicity to mice remains unclear as the publication is not very specific. However, the value of LC50 (mouse, 2 hours exposure) of 10'230 mg/m3 is used for classification according to GHS/CLP and hazard category 4 is assigned, accordingly.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
