Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via inhalation route

Link to relevant study records
Reference
Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1986
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
in lack of translation the method remains unlear
GLP compliance:
no
Species:
mouse
Route of administration:
inhalation
Duration of exposure:
2 h
Sex:
not specified
Dose descriptor:
LC50
Effect level:
10 230 mg/m³ air
Based on:
test mat.
Exp. duration:
2 h
Remarks on result:
other: details of toxic effect not reported ; only LC50 value was reported.

Details of toxic effects not reported other than lethal dose value.

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
The reliability of the data reported for acute inhalation toxicity to mice remains unclear as the publication is not very specific. However, the value of LC50 (mouse, 2 hours exposure) of 10'230 mg/m3 is used for classification according to GHS/CLP and hazard category 4 is assigned, accordingly.
Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LC50
Value:
10 230 mg/m³ air
Physical form:
inhalation: vapour

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Only one study for inhalation toxicity is available indicative for classification as category 4 for inhalation toxicity (H332) according to CLP (Regulation EC No 1272/2008). Data for acute oral or dermal toxicity is not available.