Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 273-535-2 | CAS number: 68988-63-6
Categories
- Category name:
- Tertiary amines 2
Justifications and discussions
- Category definition:
- A category of six analogues is defined for the purpose of data-gap filling of acute toxicity by the oral route (as LD50). The analogues are shown in the attached Category Report file.
- Category description:
- • The category members are tertiary amines that are > 50% structurally similar to the target chemical.
• The covered molecular log Kow range is from -2.08 to 3.69 and the target chemical is within the range. A data matrix report is listed in an attached e - Category rationale:
- The working hypothesis is that the selected analogues can be grouped together for the prediction of eye irritation. The hypothesis is based on the profilers’ outcome, which supports the assumption that the analogues are structurally related and share similar reactivity. The grouping approach is described further in the attached Prediction Report.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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