Hydrolysis product of chloro(dimethyl)octadecylsilane and silica gel

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

effects on growth of green algae

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2021

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

GLP compliance:

yes

Test material

Test material information

1

Reference substance name:

Hydrolysis product of chloro(dimethyl)octadecylsilane and silica gel

EC Number:

615-738-4

Cas Number:

72245-35-3

Molecular formula:

SiC20H43

IUPAC Name:

Hydrolysis product of chloro(dimethyl)octadecylsilane and silica gel

Sampling and analysis

Analytical monitoring:

yes

Details on sampling:

The test item was a not soluble product under the test conditions, so the test item solutions were prepared by directly adding the test item in the test medium in each replicate.

Test solutions

Vehicle:

yes

Details on test solutions:

The test medium used was OECD medium in accordance with OECD 201. It was reconstituted
with chemical reagents and deionised water.

Test organisms

Test organisms (species):

Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

72 h

Test conditions

Test temperature:

21 to 24°C controlled at ± 2°C

pH:

6.9-7.3

Nominal and measured concentrations:

100 mg/L

Reference substance (positive control):

yes

Remarks:

Potassium dichromate

Results and discussion

Effect concentrations

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat. (total fraction)

Basis for effect:

growth rate

Results with reference substance (positive control):

ErC50 72h: 0.85 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

72h ErC50 of the test item was > 100 mg/L, based on the nominal concentrations.