Registration Dossier
Registration Dossier
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EC number: 610-641-3 | CAS number: 512802-65-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 5th November 2015 to 11th May 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Identity: RM1004998
Appearance: Yellow cloudy liquid
Storage conditions: Room temperature (15 to 25°C)
Batch number: 1023R26015
Purity: 99.7% on dry basis
Expiry date: 16th September, 2017 - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- > 6.2
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not specified
- Key result
- Type:
- Pow
- Partition coefficient:
- > 1 580 000
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not specified
- Conclusions:
- The partition coefficient of the substance was determined to be >6.2.
- Executive summary:
The partition coefficient of the test substance was determined in accordance with OECD Guideline 117 and EU Method A.8 via a GLP certified laboratory. Utilising the HPLC method with an octanol-water elution, it was concluded that the substance has a log10Pow value greater than 6.2.
Reference
Description of key information
The partition coefficient of the test substance was determined in accordance with OECD Guideline 117 and EU Method A.8 via a GLP certified laboratory. Utilising the HPLC method with an octanol-water elution, it was concluded that the substance has a log10Pow value greater than 6.2.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.2
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
