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Physical & Chemical properties

Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 03/07/2012 to 24/07/2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. Substance ID is adequately specified with purity. Validation applies, with minor restrictions due to heating rate.
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
yes
Remarks:
heating rate slightly exceed maximum of 1K/min as recommended
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
yes
Remarks:
heating rate slightly exceed maximum of 1K/min as recommended
GLP compliance:
yes (incl. QA statement)
Remarks:
inspection 15-16/11/2011, decision 12/03/2012, signature 01/05/2012
Type of method:
method according to Siwoloboff
Specific details on test material used for the study:
Storage condition of test material: Refrigerator (between 0 and 10°C under nitrogen)
Boiling pt.:
284.5 °C
Atm. press.:
97.5 kPa
Decomposition:
no
Key result
Boiling pt.:
286 °C
Atm. press.:
101.325 kPa

STAGE OF TEST TEMPERATURE (K)
PRELIMINARY TEST DETERMINATION 1 DETERMINATION 2
Beginning of measurement 304 511 512
Bubbles were emerged from the capillary 562 557 558
Atmospheric pressure (kPa) 97.5 97.5 97.5

Both determinations are within the limits of accuracy (+/-2K), therefore the average value is retained: 557.5 K.

Executive summary:

The boiling point of the test substance was determined under GLP according to OECD 103/EU A2 guideline, Siwoloboff (capillary) method.

Two main runs were performed, and the mean value was retained.

The measured boiling point was 284.5°C under 97.5 kPa, and 286°C (559K) corrected to normal atmP.

Description of key information

Measured boiling point = 284.5°C under 97.5 kPa; Corrected boiling point = 286°C to normal atmP.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
286 °C

Additional information

A reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Despite minor deviation due to heating rate, it is considered as a key study. The result is retained as key data.