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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 2017-11-16 to 2017-11-17
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
13 April 2004
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Batch No.: FK650468
Purity: 100%
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
< 1
Temp.:
25 °C
Remarks on result:
other: log Pow of test item is beyond the calibrated range
Details on results:
Retention time measured for test item (1.40 min) is lower than t0 of Thiourea (2.10 min). This result shows that log Pow of test item is beyond the calibrated range.
The estimated log Pow is < 1.0.
Conclusions:
The estimated log Pow is < 1.0.
Executive summary:

The partition coefficient (log Pow) of test item was estimated using high performance liquid chromatography according to OECD 117.

Retention time measured for test item (1.40 min) is lower than t0 of Thiourea (2.10 min). This result shows that log Pow of test item is beyond the calibrated range.

The estimated log Pow is less than 1.0.

Description of key information

The estimated log Pow is less than 1.0.

Key value for chemical safety assessment

Log Kow (Log Pow):
1
at the temperature of:
25 °C

Additional information