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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 22, 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Principles of method if other than guideline:
Laser light scattering. The test was performed according to the SOP - STR 071 (Hydro 2000S) protocol.
The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
10.2 µm
St. dev.:
0
Remarks on result:
other: after 2 minutes of ultrasonic treatment. St. deviation not reported.
Percentile:
D10
Mean:
2.801 µm
St. dev.:
0
Remarks on result:
other: after 2 minutes of ultrasonic treatment. St. deviation not reported
Percentile:
D90
Mean:
38.638 µm
St. dev.:
0
Remarks on result:
other: after 2 minutes of ultrasonic treatment. St. deviation not reported.
Conclusions:
d(0.1): 2.801 µm
d(0.5): 10.200 µm
d(0.9): 38.638 µm
Executive summary:

Method:


The particle size distribution was analysed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure the size of particles. This is obtained by measuring the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.


Result:


Analysis carried out after 2 minutes of ultrasonic treatment:


d(0.1): 2.801 µm


d(0.5): 10.200 µm


d(0.9): 38.638 µm

Description of key information

Laser light scattering - MMD: 10.200 µm

Additional information