Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 279-815-0 | CAS number: 81782-77-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- not reported
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The data is taken from an abstract of an internal company report with incomplete reporting on the method; it is not possible to assess the accuracy of the information presented.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 980
- Report date:
- 1980
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- not specified
- Principles of method if other than guideline:
- Mice were exposed to 1000, 2000, 4000 or 8000 test material via the oral route. Ten mice were exposed per dose level and the rate of mortality was recorded at each.
- GLP compliance:
- no
- Test type:
- other: not reported
- Limit test:
- no
Test material
- Reference substance name:
- 4-methyl-3-decen-5-ol
- EC Number:
- 279-815-0
- EC Name:
- 4-methyl-3-decen-5-ol
- Cas Number:
- 81782-77-6
- Molecular formula:
- C11H22O
- IUPAC Name:
- 4-methyldec-3-en-5-ol
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS- Weight at study initiation: 17-22g
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- other: Gum Arabic
- Doses:
- 1000, 2000, 4000 and 8000 mg/kg
- No. of animals per sex per dose:
- 10 animals per dose
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 8 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: LD50 > 8000 g/kg
- Mortality:
- 3/10 animals died at the highest dose administered 8000.No other mortalities were recorded.
Any other information on results incl. tables
No further information on results is available.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated informationCriteria used for interpretation of results: EU
- Conclusions:
- The LD50 of the test material was recorded to be > 8000 mg/kg in mice.
- Executive summary:
In a non GLP compliant study the oral toxicity of the test material was determined by exposing mice to 100, 2000, 4000 or 8000 test via an unspecified oral route. Ten mice were exposed per dose and the rate of mortality was recorded. The LD₅₀ was determined to be > 8000 mg/kg.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
