Registration Dossier
Registration Dossier
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EC number: 237-430-5 | CAS number: 13780-39-7
Carcinogenicity
Administrative data
Description of key information
A chronic study with Titaniumtetrachloride is available.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Based on the available data of the read-across substance titanium tetrachloride, classification is not warranted. However, the material contains 1,3 -dichloropropanol (CAS # 96 -23 -1) as an impurity obove the threshold of 0.1%. This substance is subject to harmonized classification and labeling in the EU, i.e. Carc. Cat. 1B, T R45 according to Annex VI of regulation 1272/2008.
Additional information
Inhalation of Titaniumtetrachloride led to pulmonary lesions reminescent of a nuisance dust effect. The tumors that resulted from these lesions therefore do not render the substance carcinogenic.
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