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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study with acceptable restrictions

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1993

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EPA 660/8-87/011
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
Titanium dioxide
EC Number:
236-675-5
EC Name:
Titanium dioxide
Cas Number:
13463-67-7
IUPAC Name:
dioxotitanium
Details on test material:
- Name of test material (as cited in study report): Four different commercial titanium dioxide (TiO2) powders were tested each:
Titanox (TM) 1000 (98.5% TiO2), Tronox (TM) CRX (experimental, 97.0% TiO2)
, Tioxide (TM) R-FC6 (97.0% TiO2)
, Tiona (TM) RCL-69 (97% TiO2)

Sampling and analysis

Analytical monitoring:
no

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L

Any other information on results incl. tables

EC50 (48 hours) Titanox (TM) 1000   = > 1000 mg/l
EC50 (48 hours) Tronox (TM) CRX  = > 1000 mg/l
EC50 (48 hours) Tioxide (TM) R-FC6           = > 1000 mg/l
EC50 (48 hours) Tiona (TM) RCL-69= > 1000 mg/l

After 24 hours in test, all the titanium dioxide had settled to the bottom of the test vessel, except for the Tronox (TM) CRX sample. This material stayed in suspension allowing ingestion to occur for the entire 48-hour duration of this test.

Applicant's summary and conclusion