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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Description of key information

Gravimetric method was used to determine the solubility of the substance in organic solvent.The experimental value of solubility of paracetamol in ethanol at 26 degC was found to be 3000 mg/L indicating that this substance is soluble in ethanol.Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 40 mg/L at 26 degC indicating that the substance is slightly soluble in Petroleum ether.

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
2 307.69 mg/L

Additional information

Gravimetric method was used to determine the solubility of the substance in organic solvent.The experimental value of solubility of paracetamol in ethanol at 26 degC was found to be 3000 mg/L indicating that this substance is soluble in ethanol.Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 40 mg/L at 26 degC indicating that the substance is slightly soluble in Petroleum ether.The solubility value of paracetamol in ethanol at 20 degC is equivalent to a value of 2307.69 mg/L.