Disodium 4,4'-bis[[4-anilino-6-[(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]stilbene-2,2'-disulphonate

Short-term toxicity to aquatic invertebrates

Description of key information

EC50 48h Daphnia magna > 100 mg/l

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

100 mg/L

Additional information

The substance is part of the Stilbene Fluorescent Whitening Agents category, group 3. Results on analogous dihydroxyethyl derivatives of the category of Stilbene Fluorescent Whitening agents are reported: the sodium (CAS 4193-55-9), the sodium/potassium salt (CAS 70942-01-7) and the tetrasulphonated sodium salt (CAS 16324-27-9).

In the test performed on the CAS 4193-55-9 in a 48 hours screening test, according to the OECD guideline 202, a single dose was administrated at 100 mg/l (limit test) with no effect (Ciba-Geigy Ltd., 1996).

In the test on the CAS 16324-27-6, performed according to OECD 202, a nominal concentration of 100 mg/l was administered without effect; nevertheless the measured concentrations after 48h were less than 20 % the nominal and geometric mean will result in EC 50 > 53 mg/l (Ciba-Geigy Ltd., 1996).

In the test performed on the CAS 70942-01-7 the LC50 was identified as greater than 1000 mg/l (Solvias AG, 1999).

For the whole category, short term toxicity to aquatic invertebrate was tested for nine over fourteen registered substances and none of the existing tests arisen any concern for aquatic invertebrate toxicity.

As a consequence, it can be concluded that no short-term toxicity to aquatic invertebrate is expected also for CAS 17958-73-5. The result of the key study for CAS 4193-55-9 is taken as a reference for risk assessment.