Registration Dossier
Registration Dossier
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Reaction mass of (1RS,2RS,7SR,8RS,9E)-9-Ethylidene-3-oxatricyclo [6.2.1.0(2,7)] undecane and (1RS,2RS,7SR,8RS,9Z)-9-Ethylidene-3-oxatricyclo [6.2.1.0(2,7)] undecane and (1RS,2SR,7SR,8SR,10E)-10-Ethylidene-3-oxatricyclo[6.2.1.0(2,7)] undecane and (1RS,2SR,7SR,8SR,10Z)-10-Ethylidene-3-oxatricyclo [6.2.1.0(2,7)] undecane
EC number: 941-194-5 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (invertebrates)= 7.9 mg/L (C.I. 6.9-9.8 mg/L), 48hour, freshwater, OECD 202, Migchielsen 2013
NOEC (invertebrates)= 3.2 mg/L, 48hour, freshwater, OECD 202, Migchielsen 2013
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 7.9 mg/L
Additional information
The acute toxicity to Daphnia magna was carried out according to OECD 202 Daphnia sp., Acute Immobilisation Test and EU Method C.2 guidelines. A final test was performed based on the results of a preceding combined limit/range-finding test. Twenty daphnids per test group (4 replicates, 5 per replicate) were exposed to untreated control medium and to solutions representing 2.2, 4.6, 10, 22, 46 and 100% of a WSF prepared at a loading rate of 100 mg/l. Samples for analytical confirmation of actual exposure concentrations were taken at the start and the end of the 48-hour test period. Analysis of the samples taken at the start of the final test showed initial measured concentrations of 2.06, 3.50, 7.61, 17.2, 37.4 and 79.4 mg/l in test groups representing 2.2, 4.6, 10, 22, 46 and 100% WSF, respectively. The geometric mean average measured concentrations were calculated to correspond to 1.8, 3.2, 6.8, 15, 32 and 70 mg/l. The substance Daphnia magna acute immobilisation 48h-EC50 was 7.9 mg/l based on geometric mean average exposure concentrations (95% confidence interval between 6.9 and 9.8 mg/l). The substance NOEC was 3.2 mg/l based on the geometric mean average measured exposure concentration.
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