Benzenesulfonic acid, 2-amino-5-methyl-, sodium salt (1:1)

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: OECD guideline used

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1992

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

4-aminotoluene-3-sulphonic acid

EC Number:

201-831-3

EC Name:

4-aminotoluene-3-sulphonic acid

Cas Number:

88-44-8

IUPAC Name:

2-amino-5-methylbenzenesulfonic acid

Details on test material:

Dainippon Ink & Chemicals, Incorporated; purity >99%

Test organisms

Test organisms (species):

Cyprinus carpio

Study design

Test type:

flow-through

Total exposure / uptake duration:

42 d

Test conditions

Test temperature:

25 °C

Nominal and measured concentrations:

0.2 mg/l

Results and discussion

Bioaccumulation factor

Bioaccumulation factor 1

Type:

BCF

Value:

< 4

Remarks on result:

other: Conc.in environment / dose:0.2 mg/L

Bioaccumulation factor 2

Type:

BCF

Value:

< 0.4

Remarks on result:

other: Conc.in environment / dose:2 mg/L

Depuration

Elimination:

no

Any other information on results incl. tables

high exposure concentration (2.0 mg/l)
duration            14 days   21 days   28 days   42 days
concentration 
 in water (mg/l)    1.66       1.72       1.68       1.70
BCF test1           <0.4       <0.4       <0.4        <0.4
    test2            <0.4       <0.4       <0.4       <0.4

low exposure concentration (0.2 mg/l)
duration            14 days   21 days   28 days   42 days
concentration 
 in water (mg/l)    0.166     0.172      0.168     0.170
BCF test1            <4          <4         <4         <4
    test2             <4          <4         <4         <4
------------------------------------------------------------
-analytical recovery: water 103%, fish 68.3%
temperature: 25 (23-27) °C
quantative limit : high concentration - 0.31 mg/l
                   low  concentration - 0.031 mg/l
                                 fish - 0.76 ug/g
All of those results were less than 0.76 ug/g, BCF in high
concentration is <0.4 and low concentration is <4

Applicant's summary and conclusion

Conclusions:

The results were less than quantitative limits BFC was < 4 (0.2 mg/l) and < 0.4 (2.0 mg/l)