N-[3-(dimethylamino)propyl]dodecanamide N-oxide

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

10 Feb - 29 Apr 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

not specified

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

not specified

GLP compliance:

yes

Type of method:

effusion method: isothermal thermogravimetry

Test material

Test material information

Constituent 1

Reference substance name:

N-[3-(dimethylamino)propyl]dodecanamide N-oxide

EC Number:

263-218-7

EC Name:

N-[3-(dimethylamino)propyl]dodecanamide N-oxide

Cas Number:

61792-31-2

Molecular formula:

C17H36N2O2

IUPAC Name:

N-[3-(dimethylamino)propyl]dodecanamide N-oxide

Results and discussion

Vapour pressure

Vapour pressure 1

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

< 0.002 Pa

Vapour pressure 2

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

< 0.006 Pa

Any other information on results incl. tables

Results:

In the range of 80°C and 110°C a log p versus 1/T curve for the test item could not be determined since the coefficient of correlation (r) was < 0.99 (data is archived in the raw data). From 120 °C a non-linear weight loss was observed. This was most likely due to reaction and/or decomposition of the test item. Since no accurate vapour pressure could be calculated from the obtained results, the weight losses of the test item were compared with the results of hexachlorobenzene at the temperatures of 100 °C and 110 °C. Since the weight loss of the test item was lower than the weight loss of the reference compound, the vapour pressure of the test item is considered to be below the vapour pressure of hexachlorobenzene.

Vapour Pressure of the Test Item-

@ 20 deg C: < 1.5E-03 Pa (< 1.1E-05 mm Hg)

@ 25 deg C: < 6.3E-03 Pa (< 4.7E-05 mm Hg)

Conclusion:

The isothermal TGA effusion method was applied for the determination of the vapour pressure of N-[3-(dimethyloxidoamino)propyl]-dodecanamide (freeze dried). The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:

@ 20 deg C: < 1.5E-03 Pa (< 1.1E-05 mm Hg)

@ 25 deg C: < 6.3E-03 Pa (< 4.7E-05 mm Hg)