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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

The Terpene hydrocarbon alcohols are readily biodegradable based on read across from Terpineol multi, which is readily biodegradable in study according to OECD TG 310.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:

Additional information

Biodegradability in water is assessed based on read-across from Terpineol multi to Terpene hydrocarbon alcohols. The executive summary of the source information is presented below, followed by the read-across rationale.


Biodegradation of Terpene hydrocarbon alcohols based on read-across from data available for Terpineol multi (CAS# 8000-41-7).

Introduction and hypothesis for the analogue approach

Terpene hydrocarbon alcohols have the following constituent types of substances: Solely hydrocarbons-terpene type, Alcohol-type, Ketone-type and Ether-type all having a saturated or unsaturated cyclic hydrocarbon backbone. For this substance no biodegradation information is available. In accordance with Article 13 of REACH, lacking information can be generated by other means than experimental testing, i.e. applying alternative methods such as QSARs, grouping and read-across. For assessing the biodegradability information from the constituent Terpinolene is used, which can represent the Terpene hydrocarbon alcohols.

Hypothesis: Terpene hydrocarbon alcohols have the same biodegradability potential as Terpineol multi.

Available information: Terpineol multi is readily biodegradable in the OECD TG 310, Rel. 1 at a concentration of 26 mg/L, 80% biodegradation was achieved, meeting the 10-day window.

Target chemical and source chemical(s)

Constituent types of the target substance and chemical structures of the source substances are shown in the data matrix, including physico-chemical properties and biodegradability information, thought relevant for read across.

Purity / Impurities

Constituent types of the target substance are covered by the presented constituent types, there are no other constituent that impacts the biodegradability potential.

Analogue approach justification

According to Annex XI 1.5 read across can be used to replace testing when the similarity can be based on a common backbone and a common functional group.When using read across the result derived should be applicable for C&L and/or risk assessment and it should be presented with adequate and reliable documentation, which is presented below.

Analogue selection: For the Terpene hydrocarbon alcohols its key constituent Terpineol (in the form of Terpineol multi) is selected as analogue for the other constituents and for this substance biodegradation information is available.

Structural similarities and differences: The Terpene hydrocarbon alcohols consist at least of 40% Terpineol and therefore have the same structure. All and other constituents have similar backbones, mostly containing a hydrocarbon cyclohexyl/hexene group with a (branched) alkyl chain, and/or alkyl bridge over the cyclohexyl ring.

Bioavailability: Terpene hydrocarbon alcohols constituents are all bioavailable based on molecular weight and log Kow.

Biodegradable fragments: The Terpene hydrocarbon alcohols have similar backbones and therefore have similar biodegradable fractions.

Information on other constituents: Terpinolene (Solely hydrocarbon type Cas no 586-62-9 and EC No. 209-578-0) and Camphor (Ketone type Cas no. 76-22-2; EC no. 200-945-0) are ready biodegradable based on information from the ECHA website.

Uncertainty of the prediction: There are no uncertainties other than those addressed above.

Data matrix

The relevant information on physico-chemical properties and toxicological characteristics are presented in the Data Matrix.

Conclusions on biodegradability for hazard and risk assessment

For the Terpene hydrocarbon alcohols no biodegradation information is available. Read-across is used to fill this data gap. When using read-across, the result derived should be applicable for C&L and/or risk assessment, and be presented with adequate and reliable documentation. This documentation is presented in the current text. For the key constituent Terpineol multi and analogue for other constituents, data is available from a reliable study according to OECD TG 310 in which the substance was found to be readily biodegradable. This information can be used for read across.

Final conclusion:The Terpene hydrocarbon alcohols arereadily biodegradable.

Data matrix supporting the ready biodegradability information relevant for read across to the Terpene hydrocarbon alcohols from Terpineol multi

Terpene hydrocarbon alcohols

Terpineol hydrocarbon alcohols

Terpineol multi





Not applicable


(α-Terpineol and γ-Terpineol)


Not applicable

98-55-5 and 8000-41-7

EC No.


202-680-6 /232-268-1

Reach registration



Molecular weight



Phys-chem properties






Log Kow

3.3-5.5, IFF


Identity, Constituent type (%)



Solely hydrocarbons



Terpinolene type



Alcohol type



Tertiary alcohols (e.g. Terpineol)



Secondary alcohols (e.g. Borneol)



Ketone type






Ether type



Aromatic ether type



Environmental fate




Readily biodegradable

(Read across)

Readily biodegradable

(OECD TG 310)