Registration Dossier
Registration Dossier
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EC number: 807-677-9 | CAS number: 817204-32-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Study period:
- 2014
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
Materials and methods
- Principles of method if other than guideline:
- QSAR (Toxtree)
- Test type:
- other: QSAR (Toxtree)
Test material
- Reference substance name:
- 2’Deoxy-2’-fluoro-2’-methyl-N-(phenylcarbonyl)-3’,5’-bis-O-(phenylcarbonyl)cytidine
- EC Number:
- 807-677-9
- Cas Number:
- 817204-32-3
- Molecular formula:
- C31H26FN3O7
- IUPAC Name:
- 2’Deoxy-2’-fluoro-2’-methyl-N-(phenylcarbonyl)-3’,5’-bis-O-(phenylcarbonyl)cytidine
Constituent 1
Results and discussion
Any other information on results incl. tables
Based on QSAR results (Toxtree) and expert judgement, the substance is estimated to have an LD50 of 300 - 2000 mg/kg (oral, rat)
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Classified as Acute toxicity 4 (oral) based on QSAR and expert judgement.
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