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EC number: 917-780-1 | CAS number: 1176286-43-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No short-term toxicity effects within the range of water solubility expected.
Key value for chemical safety assessment
Additional information
No study is available on short-term toxicity of fatty acids, soybean oil, conjugated (CAS 1176286 -43 -3) with fish.
Therefore ecotoxicological effects are predicted from adequate and reliable data for source substance(s) by read-across to the target substance within the group applying the group concept in accordance with Annex XI, Item 1.5, of Regulation (EC) No 1907/2006.
As the main constituents of the mixture are C16, C18', C18'' conjugated and C18'', read-across is performed to the saturated palmitic acid C16 (CAS 57 -10 -3) and the unsaturated oleic acid C18' (CAS 112 -80 -1). Oleic acid contains one double-bond and is, as the blend under discussion and the palmitic acid, a member of the fatty acids category. Furthermore, a supporting read across is performed to fatty acids, tall oil (CAS 61790 -12 -3), since the main components of this fatty acids mixture are also unsaturated C18 components (50 -60% C18', 35 -40% C18'').
The single-chain homologue palmitic acid C16 was tested on rice fish, medaka (Oryzias latipes) (Ministry of the Environment, Government of Japan, 2000). The test followed the OECD-guideline 203 and was conducted according to GLP requirements in a semi-static system. The nominal test concentration of the limit-test was 10 mg/L resulting in a mean measured concentration of 6.9 mg/L (solvent used). As the substance was presolved in a vehicle the given concentration is above the measured water solubility of 0.82 mg/L in the test medium. After 96 h exposure an LC50 of > 6.9 mg/L was reported. Thus no mortalities within the range of water solubility could be detected.
In a further study provided from the Ministry of the Environment, Government of Japan (2003), oleic acid C18' (CAS 112 -80 -1) was tested as limit test according to OECD 203 under GLP-conditions. In the semi-static test the LC50 (96 h) was reported to be > 2.5 mg/L based on mean measured concentrations (corresponding to > 3.6 mg/L based on nominal concentrations), no solvent was used in this test. Thus no effect within the range of water solubility could be detected.
The third study on toxicity to fish with fatty acids, tall oil was conducted according to OECD 203 under GLP conditions (Pine Chemical Association, 2004). Fathead minnow (Pimephales promelas) was exposed to water accomodated fractions (WAF) of 1, 10, 100 and 1000 mg/L (nominal). Since no mortality was observed up to the highest loading rate a LL50 (96 h) of > 1000 mg/L was stated. Thus no effect up to the limit of water solubility could be detected.
Summarising the listed results the conclusion can be drawn that short-term effects on fish of fatty acids, soybean oil, conjugated are not expected up to the limit of water solubility.
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