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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

No data are available for chloro(methyl)silane. A 48-hour EC50 of 124 mg/L has however been determined for the effects of a read-across substance, Trimethylsilanol (CAS 1066-40-6), on mobility of Daphnia magna.  A NOEC of <60 mg/L has been determined in the same test. A 48-hour EC50 value of >117 mg/L and NOEC of ≥117mg/L have been determined for the effects of a second read-across substance, dimethylsilanediol, 1066-42-8, on mobility of D. magna. The results of the test with trimethylsilanol (CAS 1066-40-6) have been selected as the key results because they are definitive values.

Key value for chemical safety assessment

Additional information

No test data for short-term toxicity to aquatic invertebrates are available for Chloro(methyl)silane. However reliable data for short-term toxicity to invertebrates are available for the related substances Dimethylsilanediol, 1066-42-8, and Trimethylsilanol, 1066-40-6. The hydrolysis half-life of Chloro(methyl)silane indicates that, under conditions relevant to the short-term invertebrate test, hydrolysis to Dimethylsilanol and hydrogen chloride will occur. The properties of hydrogen chloride are well characterised and are discussed in the CSR. Its effects on aquatic organisms are limited to those that result from changes to pH in unbuffered media. Read-across from trimethylsilanol and dimethylsilanediol to dimethylsilanol is appropriate because all are small molecule alkylsilanols containing Me-Si and HO-Si groups; their properties are expected to be similar.