Registration Dossier
Registration Dossier
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Reaction mass of 5,5'-{(phenylmethanediyl)bis[benzene-4,1-diyl-diazene-2,1-diyl]}bis{1-[3-(dimethylamino)propyl]-4-methyl-6-oxo-3-(pyridinium-1-yl)-1,6-dihydropyridin-2-olate} hydrochloride and 5,5’-[3,4’-(phenylmethanediyl)diphenylene]bis(diazene-2,1-diyl)bis{1-[3-(dimethylamino)propyl]-4-methyl-6-oxo-3-(pyridinium-1-yl)-1,6-dihydropyridin-2-olate} hydrochloride
EC number: 700-312-3 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The substance registered has an acute Daphnia toxicity EC50 of 7.2 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 7.2 mg/L
Additional information
A valid Daphnia toxicity study was conducted with the analogue substance. The applicability of the read across approach had been confirmed by the registrant via an expert statement (see IUCLID chapter 13).
The 48‑hour EC50 of the analogue substance was calculated to be 7.4 mg/L with a 95% confidence interval of 5.6 -9.7 mg/L.
Based on the same molarity, for the substance registered the resulting EC50 was 7.2 mg/L. This result basically was being confirmed by a non-key study with the substance registered (estimated EC50 = 10 mg/L).
The result supports the classification of the substance registered as toxic to the aquatic environment.
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