Registration Dossier
Registration Dossier
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EC number: 453-490-7 | CAS number: -
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Only summary of the results available
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
- Type of study / information:
- Skin irritating potential in humans
- Endpoint addressed:
- skin irritation / corrosion
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The test substance was applied as supplied under occlusive patch during 24 h, on the upper back of 11 volunteers.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- -
- EC Number:
- 453-490-7
- EC Name:
- -
- Molecular formula:
- Not applicable (UVCB)
- IUPAC Name:
- 2-[(decanoyloxy)methyl]-3-[3-(heptanoyloxy)-2-[(octanoyloxy)methyl]-2-{[(3,5,5-trimethylhexanoyl)oxy]methyl}propoxy]-2-[(octanoyloxy)methyl]propyl decanoate; 3-[3-(heptanoyloxy)-2,2-bis({[(3,5,5-trimethylhexanoyl)oxy]methyl})propoxy]-2-[(heptanoyloxy)methyl]-2-[(octanoyloxy)methyl]propyl decanoate
Constituent 1
Method
- Ethical approval:
- not specified
- Details on study design:
- no data
Results and discussion
- Results:
- No skin reaction was observed in any of the subjects.
Primary skin irritation index = 0.0
Applicant's summary and conclusion
- Conclusions:
- Not irritating
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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